Opportunity Information: Apply for PAR 18 228

The NIH funding opportunity PAR 18-228, titled "Pilot Studies to Detect and Prevent Suicide Behavior, Ideation and Self-Harm in Youth in Contact with the Juvenile Justice System (R34 Clinical Trial Required)," supports early-stage, pilot clinical trial research focused on reducing suicide-related outcomes among young people who interact with the juvenile justice system. The core idea is to test the effectiveness of approaches that do two things together: (1) improve detection of suicide risk, suicidal thoughts, and non-suicidal self-injury (NSSI), and (2) deliver practical interventions aimed at preventing escalation to self-harm or suicide behavior. Rather than funding large definitive trials, this R34 mechanism is geared toward pilot testing and building a solid evidence base and implementation pathway for larger follow-on studies.

A key feature of this opportunity is its emphasis on real-world juvenile justice touchpoints where prevention can realistically happen. The FOA highlights that risk detection and prevention opportunities begin very early, including first contacts such as police interactions or intake interviews, and continue across multiple settings and decision points like pre-trial detention, juvenile or family court proceedings, court disposition, placement decisions, and ongoing care in residential facilities or community supervision and service settings. In practice, this means applicants are encouraged to design strategies that can be embedded throughout the youth justice pathway, including moments that are often chaotic or time-pressured, where staff need usable tools and clear workflows.

The FOA also pushes applicants to focus on interventions that are feasible in typical service environments using commonly available staff, resources, and infrastructure. In other words, the goal is not to create an idealized program that only works with highly specialized clinicians or exceptional funding. Instead, NIH is looking for combined detection-and-intervention strategies that juvenile justice agencies, courts, detention centers, and community programs could realistically deliver through existing personnel and routine operations. This implementation-oriented focus is meant to increase the chances that strategies proven effective in the pilot phase can be adopted more widely across diverse jurisdictions and settings, ultimately reducing suicide and self-harm risk in this high-vulnerability population.

Administratively, this is a discretionary grant program within the NIH health research portfolio (CFDA 93.242). The funding instrument is a grant, and the award ceiling listed is $225,000. The opportunity record indicates an original closing date of 2021-01-07, and a creation date of 2017-11-17, which is helpful for understanding the timeframe of the announcement and that applicants should verify current status and any reissued or updated versions if they are planning a submission now.

Eligibility is broad and includes many types of U.S.-based organizations and governmental entities. Eligible applicants include state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities/Indian housing authorities; Native American tribal organizations other than federally recognized tribal governments; nonprofits with and without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories); for-profit organizations other than small businesses; small businesses; and other eligible entities. The FOA also explicitly calls out additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions; Asian American, Native American, and Pacific Islander Serving Institutions (AANAPISIs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); faith-based or community-based organizations; eligible federal agencies; regional organizations; U.S. territories or possessions; and Indian/Native American tribal governments that are not federally recognized.

At the same time, the FOA places clear limits on foreign involvement. Non-domestic (non-U.S.) entities (foreign organizations and foreign institutions) are not eligible to apply. Non-domestic components of U.S. organizations are also not eligible to apply. In addition, foreign components, as NIH defines them in the NIH Grants Policy Statement, are not allowed under this opportunity. Practically, that means the applicant organization and the work supported by the award must remain domestic in scope and structure under NIH policy for this FOA.

Overall, this opportunity is aimed at generating actionable, scalable evidence on how to identify suicide risk and deliver prevention support for justice-involved youth across the points in the system where youth are assessed, detained, adjudicated, placed, and supervised. The strongest-fit projects are likely to be those that pair a workable detection approach (such as structured screening and risk triage processes) with an intervention that can be delivered with routine staffing and resources, while also paying attention to implementation in the messy realities of juvenile justice settings.

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Pilot Studies to Detect and Prevent Suicide Behavior, Ideation and Self-Harm in Youth in Contact with the Juvenile Justice System (R34 Clinical Trial Required)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242.
  • This funding opportunity was created on 2017-11-17.
  • Applicants must submit their applications by 2021-01-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $225,000.00 in funding.
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
Apply for PAR 18 228

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FAQs: NIH PAR-18-228 (R34) Pilot Studies to Detect and Prevent Suicide Behavior, Ideation and Self-Harm in Justice-Involved Youth

What is PAR-18-228?

PAR-18-228 is an NIH funding opportunity titled "Pilot Studies to Detect and Prevent Suicide Behavior, Ideation and Self-Harm in Youth in Contact with the Juvenile Justice System (R34 Clinical Trial Required)." It supports early-stage, pilot clinical trial research focused on reducing suicide-related outcomes among youth who interact with the juvenile justice system.

What is the main goal of this funding opportunity?

The main goal is to pilot test practical, real-world strategies that combine (1) improved detection of suicide risk, suicidal thoughts, and non-suicidal self-injury (NSSI) and (2) interventions designed to prevent escalation to self-harm or suicide behavior among justice-involved youth.

What kind of research does this FOA fund?

This FOA funds early-stage pilot clinical trial research. It is designed to build evidence and an implementation pathway for larger follow-on studies, rather than supporting large, definitive trials.

Is a clinical trial required under this opportunity?

Yes. The funding opportunity is designated "R34 Clinical Trial Required," meaning the supported projects are expected to include a clinical trial component as part of the pilot study.

What does the R34 mechanism mean in this context?

The R34 mechanism is oriented toward pilot testing. Under this FOA, it is used to evaluate feasibility and early effectiveness of combined detection-and-intervention approaches and to generate actionable evidence that can support later, larger-scale studies.

What populations does the FOA focus on?

The focus is on youth who are in contact with the juvenile justice system, particularly those at risk for suicide behavior, suicidal ideation, and non-suicidal self-injury (NSSI).

What outcomes is the FOA trying to reduce?

The FOA is aimed at reducing suicide-related outcomes, including suicide behavior, suicidal ideation (suicidal thoughts), and self-harm, including non-suicidal self-injury (NSSI), among justice-involved youth.

What is meant by "combined detection-and-intervention strategies"?

It refers to approaches that do two things together: first, they improve detection (such as identifying risk, ideation, or NSSI through screening or triage), and second, they provide an intervention intended to prevent escalation to self-harm or suicide behavior.

Where in the juvenile justice system does NIH expect these strategies to be used?

The FOA emphasizes real-world juvenile justice touchpoints where prevention can realistically happen, including early points of contact and multiple decision points across the youth justice pathway.

What are examples of "touchpoints" mentioned in the FOA?

The FOA highlights touchpoints such as first contacts (including police interactions or intake interviews), pre-trial detention, juvenile or family court proceedings, court disposition, placement decisions, and ongoing care in residential facilities or community supervision and service settings.

Does the FOA encourage interventions at early points of contact?

Yes. The FOA explicitly notes that opportunities for risk detection and prevention begin very early, including first contacts like police interactions and intake interviews.

Does the FOA support projects designed for time-pressured or chaotic settings?

Yes. The FOA recognizes that many juvenile justice moments are chaotic or time-pressured and encourages strategies that can be embedded into routine workflows with usable tools and clear processes for staff.

How important is real-world feasibility and implementation?

Feasibility in typical service environments is a major emphasis. NIH is looking for strategies that can be delivered through existing personnel and routine operations, rather than approaches that require highly specialized clinicians or unusually high levels of funding.

What types of staff or resources should the intervention rely on?

The FOA encourages interventions that can be implemented with commonly available staff, resources, and infrastructure in juvenile justice agencies, courts, detention centers, and community programs.

Does this funding opportunity support "idealized" programs that require specialized staffing?

The FOA signals that the goal is not to create a program that only works in ideal conditions with highly specialized clinicians or exceptional funding. It prioritizes workable approaches suitable for routine service settings.

What is the award ceiling for this opportunity?

The listed award ceiling is $225,000.

What is the CFDA number associated with this program?

The opportunity is listed under CFDA 93.242.

What type of funding instrument is used?

The funding instrument is a grant.

Is this a discretionary grant program?

Yes. The opportunity is described as a discretionary grant program within the NIH health research portfolio.

What are the key dates shown in the opportunity record?

The opportunity record indicates a creation date of 2017-11-17 and an original closing date of 2021-01-07.

What should applicants do given the closing date listed?

Because the record shows an original closing date of 2021-01-07, applicants planning to submit now should verify the current status of the opportunity and check whether NIH has reissued or updated the FOA.

Who is eligible to apply?

Eligibility is broad and includes many U.S.-based organizations and governmental entities, including multiple categories of government bodies, educational institutions, tribal entities, nonprofits, and for-profit organizations.

Which government entities are eligible applicants?

Eligible governmental applicants include state, county, city or township governments; special district governments; and eligible federal agencies.

Are U.S. higher education institutions eligible?

Yes. Eligible applicants include public and state-controlled institutions of higher education and private institutions of higher education, as well as several designated categories of serving institutions.

What types of designated higher education institutions are specifically called out as eligible?

The FOA explicitly calls out eligibility for Alaska Native and Native Hawaiian Serving Institutions; Asian American, Native American, and Pacific Islander Serving Institutions (AANAPISIs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); and Tribally Controlled Colleges and Universities (TCCUs).

Are tribal governments and tribal organizations eligible?

Yes. Eligible applicants include federally recognized Native American tribal governments, and the FOA also identifies Indian/Native American tribal governments that are not federally recognized as eligible, as well as Native American tribal organizations other than federally recognized tribal governments.

Are nonprofits eligible to apply?

Yes. Eligible applicants include nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status (excluding institutions of higher education within those nonprofit categories).

Are for-profit organizations eligible?

Yes. Eligible applicants include for-profit organizations other than small businesses, as well as small businesses.

Are faith-based or community-based organizations eligible?

Yes. The FOA explicitly lists faith-based or community-based organizations among the additional eligible applicant categories.

Are regional organizations eligible?

Yes. Regional organizations are explicitly included in the additional eligible applicant categories.

Are U.S. territories or possessions eligible?

Yes. U.S. territories or possessions are included among the additional eligible applicant categories.

Are public housing authorities eligible?

Yes. Public housing authorities and Indian housing authorities are included among the eligible applicants.

Are foreign organizations eligible to apply?

No. Non-domestic (non-U.S.) entities, including foreign organizations and foreign institutions, are not eligible to apply under this opportunity.

Can a U.S. organization apply if the project has a non-U.S. component?

No. Non-domestic components of U.S. organizations are not eligible to apply, and foreign components (as defined by NIH in the NIH Grants Policy Statement) are not allowed under this FOA.

Does the FOA allow any foreign components as NIH defines them?

No. The FOA states that foreign components, as NIH defines them in the NIH Grants Policy Statement, are not allowed.

What does the FOA emphasize about scaling and broader adoption?

The FOA is implementation-oriented, emphasizing strategies that fit routine operations so that approaches proven effective in the pilot phase have a clearer path to adoption across diverse jurisdictions and settings.

What types of projects are likely to be the strongest fit?

The strongest-fit projects are likely to pair a workable detection approach (such as structured screening and risk triage processes) with an intervention that can be delivered using routine staffing and resources, while accounting for implementation realities across juvenile justice settings.

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