Opportunity Information: Apply for RFA AG 20 023
The Exploratory Grant for NIA Alzheimer's Disease Research Center (P20 Clinical Trial Not Allowed), funding opportunity number RFA-AG-20-023, is a National Institutes of Health (NIH) grant designed to help organizations lay the groundwork for a full Alzheimer's Disease Research Center (ADRC) award under the P30 mechanism. The main idea is to support early-stage planning and coordinated start-up activities that build the collaborations, shared resources, and overall research infrastructure an institution would need to successfully operate an ADRC. In practical terms, this opportunity is meant for groups that are not yet running a P30-level center but want to organize the people, systems, and institutional capacity required to become competitive for one.
The purpose of the award is not to fund a mature, fully operating center right away, but to fund the steps that make a future center possible. That includes initiating collaborative activities across departments or partner institutions, establishing governance and administrative structures, developing core capabilities (such as standardized procedures, data systems, recruitment pipelines, or clinical and research coordination processes), and creating the operational framework that aligns with what an NIH-funded ADRC is expected to have. Because the announcement is explicitly "Clinical Trial Not Allowed," the work proposed under this P20 should not involve conducting clinical trials; applicants need to shape the project around infrastructure development, planning, coordination, and other non-trial activities that strengthen readiness for a P30 application.
This is a discretionary grant in the Health funding activity category, listed under CFDA number 93.866. The agency is NIH, and the opportunity was created on May 30, 2019, with an original closing date of October 9, 2019. The listed award ceiling is $750,000. The source information does not specify the expected number of awards in the provided field, so applicants would typically look to the full announcement for any details on anticipated funding levels or paylines beyond the ceiling amount.
Eligibility is broad across U.S.-based entities and includes multiple levels of government (state, county, city or township, and special district governments), independent school districts, public and state-controlled institutions of higher education, private institutions of higher education, federally recognized Native American tribal governments, and Native American tribal organizations that are not federally recognized tribal governments. It also includes public housing authorities/Indian housing authorities, nonprofit organizations both with and without 501(c)(3) status (as long as they are not institutions of higher education in those nonprofit categories), for-profit organizations other than small businesses, and small businesses. The announcement also highlights additional eligible applicant types such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible agencies of the federal government, and U.S. territories or possessions.
At the same time, the opportunity is clearly limited to domestic applicants and domestic project components. Non-domestic (non-U.S.) entities, including foreign organizations and foreign institutions, are not eligible to apply. In addition, non-domestic components of U.S. organizations are not eligible, and foreign components, as NIH defines them in the NIH Grants Policy Statement, are not allowed. In other words, the work supported by this grant must be planned and carried out without foreign components, and applicants need to structure collaborations and project activities accordingly.
Overall, this FOA is best read as a stepping-stone mechanism: it supports institutions that are building toward an ADRC by funding the early infrastructure and coordination work needed to develop an Alzheimer-focused research center that can later meet the expectations of the P30 ADRC program.Apply for RFA AG 20 023
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Exploratory Grant for NIA Alzheimers Disease Research Center (P20 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866.
- This funding opportunity was created on 2019-05-30.
- Applicants must submit their applications by 2019-10-09. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $750,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is this funding opportunity?
This opportunity is the Exploratory Grant for NIA Alzheimer's Disease Research Center (P20 Clinical Trial Not Allowed), funding opportunity number RFA-AG-20-023. It is a National Institutes of Health (NIH) grant intended to support early-stage planning and start-up activities that help an organization prepare to compete for a full Alzheimer's Disease Research Center (ADRC) award under the P30 mechanism.
What is the main goal of the P20 exploratory grant?
The main goal is to help institutions lay the groundwork for a future P30 ADRC by funding coordinated planning, collaboration-building, and research infrastructure development. It is designed for groups that are not yet operating a P30-level center but want to organize the people, systems, and institutional capacity needed to become competitive for one.
Is this grant meant to fund a fully operational Alzheimer's Disease Research Center?
No. The award is not intended to fund a mature, fully operating ADRC right away. Instead, it supports the steps that make a future center possible, such as setting up governance, administrative structures, and shared resources.
What kinds of activities does this grant support?
Based on the information provided, the grant supports early-stage planning and coordinated start-up activities, including:
- Initiating collaborative activities across departments and/or partner institutions
- Establishing governance and administrative structures
- Developing core capabilities and operational frameworks expected of an NIH-funded ADRC
- Creating or strengthening standardized procedures, data systems, recruitment pipelines, and coordination processes (clinical and research coordination processes) as part of infrastructure development
- Building shared resources and overall research infrastructure needed to run a future ADRC
Are clinical trials allowed under this funding opportunity?
No. The announcement is explicitly labeled "Clinical Trial Not Allowed." Applicants should not propose conducting clinical trials under this P20 award and should instead focus on infrastructure development, planning, and coordination activities that strengthen readiness for a later P30 ADRC application.
What does "Clinical Trial Not Allowed" mean for project design?
It means the work proposed should be shaped around non-trial activities such as organizing collaborations, developing governance and administrative processes, building data and operational systems, and other planning/start-up work. The proposed scope should avoid conducting clinical trials as part of the funded activities.
Who is the funding agency?
The funding agency is the National Institutes of Health (NIH).
What is the funding opportunity number?
The funding opportunity number is RFA-AG-20-023.
What is the CFDA number and funding activity category?
The opportunity is listed under CFDA number 93.866 and is categorized as a discretionary grant in the Health funding activity category.
What is the maximum award amount (award ceiling)?
The listed award ceiling is $750,000.
Does the provided information state how many awards NIH expects to make?
No. The source information does not specify the expected number of awards in the provided field. Applicants would typically consult the full announcement for details on anticipated award counts or other funding expectations beyond the ceiling amount.
When was this opportunity created and what was the original closing date?
The opportunity was created on May 30, 2019, and the original closing date was October 9, 2019.
Who is eligible to apply?
Eligibility is broad for U.S.-based entities. The information provided lists eligible applicants including:
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and state-controlled institutions of higher education
- Private institutions of higher education
- Federally recognized Native American tribal governments
- Native American tribal organizations (other than federally recognized tribal governments)
- Public housing authorities/Indian housing authorities
- Nonprofit organizations with 501(c)(3) status (other than institutions of higher education in that category)
- Nonprofit organizations without 501(c)(3) status (other than institutions of higher education in that category)
- For-profit organizations other than small businesses
- Small businesses
Are specific institution types explicitly highlighted as eligible?
Yes. The announcement highlights additional eligible applicant types such as:
- Alaska Native and Native Hawaiian Serving Institutions
- Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)
- Hispanic-serving Institutions
- Historically Black Colleges and Universities (HBCUs)
- Tribally Controlled Colleges and Universities (TCCUs)
- Faith-based or community-based organizations
- Regional organizations
- Eligible agencies of the federal government
- U.S. territories or possessions
Are non-U.S. (foreign) organizations eligible to apply?
No. The opportunity is limited to domestic applicants. Non-domestic (non-U.S.) entities, including foreign organizations and foreign institutions, are not eligible to apply.
Can a U.S. organization include a foreign component in the project?
No. Non-domestic components of U.S. organizations are not eligible, and foreign components (as defined by NIH in the NIH Grants Policy Statement) are not allowed. The work supported by this grant must be planned and carried out without foreign components.
Can the project include collaborations with partners outside the United States?
The information provided states that foreign components are not allowed and non-domestic components are not eligible. Applicants would need to structure collaborations and project activities so the supported work has no foreign components.
What is the relationship between this P20 award and the P30 ADRC mechanism?
This P20 is described as a stepping-stone mechanism. It supports early infrastructure and coordination work intended to position an institution to later apply for and operate an ADRC funded under the P30 mechanism.
What types of infrastructure might an applicant develop under this award?
The provided information gives examples of infrastructure-related activities, such as developing standardized procedures, data systems, recruitment pipelines, and clinical/research coordination processes, along with establishing governance and administrative structures and shared resources that align with what an NIH-funded ADRC is expected to have.
Is this opportunity appropriate for organizations that already run a P30-level center?
The information describes this opportunity as intended for groups that are not yet running a P30-level center but want to build the collaborations, shared resources, and institutional capacity needed to become competitive for one.
What should applicants focus on to stay aligned with the intent of the FOA?
Applicants should focus on planning, coordinated start-up activities, and building ADRC-ready infrastructure (governance, administrative systems, shared resources, and operational frameworks) while avoiding clinical trials and avoiding any foreign components.
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