Opportunity Information: Apply for RFA DP 21 002
The Epidemiologic Cohort Study of Interstitial Cystitis (IC) funding opportunity (RFA DP 21 002) is a CDC cooperative agreement designed to build a clearer, population-focused understanding of interstitial cystitis over time and to turn that evidence into practical public health improvements. The core goal is to follow a well-defined group of people with IC longitudinally so researchers can generate more reliable estimates of IC incidence, describe who is affected and how the condition presents clinically, and document how IC influences health and daily functioning as time passes. The emphasis is not only on observing disease patterns, but on producing findings that are actionable for patients, providers, and public health systems.
A central scientific objective is to develop incidence estimates and to map demographic and clinical patterns of IC. This includes characterizing how IC appears and progresses across different groups, potentially capturing variation by factors such as age, sex, race and ethnicity, geography, and other social or health-related characteristics that may shape risk, diagnosis, symptom severity, and outcomes. By following participants over time, the study is positioned to measure changes in symptoms, comorbidities, healthcare utilization, and broader impacts in a way that one-time surveys cannot. The longitudinal design also supports documenting the cumulative burden of IC, including how it affects quality of life, functional status, and overall health trajectories.
A second major pillar of the opportunity is translation of scientific knowledge into public health practice. The NOFO explicitly calls for using insights from this cohort study and prior IC research to support real-world improvements in three areas: patient strategies that can improve quality of life, provider and patient awareness and education, and approaches to medical and self-management of IC. In practice, that means the funded work is expected to do more than publish findings; it should also help shape educational materials, awareness strategies, and tools or recommendations that patients and clinicians can use to manage IC more effectively. The translation component is meant to strengthen the bridge between research evidence and routine care, helping reduce gaps in understanding, recognition, and management of IC.
The opportunity also highlights strengthening linkages across clinical, community, and public health settings, with a specific intent to better reach groups that are disproportionately impacted by IC. This suggests an expectation that the awardee will pay attention to equity and access, including identifying barriers to diagnosis, care, and self-management support, and building partnerships that can improve reach and relevance of interventions or educational efforts. The overall framing encourages coordination across stakeholders rather than isolating the work within a single research environment.
Administratively, this is a discretionary funding opportunity offered by the U.S. Department of Health and Human Services through the Centers for Disease Control and Prevention (CDC). The funding instrument is a cooperative agreement, which typically indicates substantial federal involvement beyond standard grant oversight, such as collaboration on technical direction, performance monitoring, and alignment with CDC priorities. The program is listed under CFDA 93.283. The award ceiling is $900,000, with one expected award, reflecting a single, concentrated effort to conduct and translate this cohort-based epidemiologic work. Eligible applicants are broad and include various levels of government, public and private institutions of higher education, tribal governments and tribal organizations, public housing authorities/Indian housing authorities, for-profit organizations (including small businesses), and other specified entities, subject to any additional eligibility clarifications in the full announcement. The notice was created on November 10, 2020, with an original application deadline of January 14, 2021, and required electronic submission by 11:59 p.m. ET on the due date.
Taken together, this NOFO supports a comprehensive approach: sustained follow-up of a defined IC cohort to improve basic epidemiologic understanding, paired with a deliberate plan to convert what is learned into education, awareness, and management strategies that can measurably improve the lives of people living with interstitial cystitis and strengthen the broader public health response.Apply for RFA DP 21 002
- The Department of Health and Human Services, Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Epidemiologic Cohort Study of Interstitial Cystitis" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.283.
- This funding opportunity was created on Nov 10, 2020.
- Applicants must submit their applications by Jan 14, 2021 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $900,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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