NIDDK Hematology Central Coordinating Center (U24 Clinical Trial Not Allowed) | RFA DK 19 013

Opportunity Information: Apply for RFA DK 19 013

The NIDDK Hematology Central Coordinating Center (HCCC) funding opportunity (RFA-DK-19-013) is an NIH cooperative agreement (U24; clinical trial not allowed) meant to create a central hub that supports and connects a national network focused on nonmalignant hematology. The award is designed to coordinate the NIDDK Hematology Centers Program, in which the HCCC works closely with approximately 4 to 5 Cooperative Centers of Excellence in Hematology (CCEHs). The overall purpose is to strengthen and accelerate multidisciplinary research aimed at understanding normal hematopoiesis and improving prevention, diagnosis, and treatment approaches for nonmalignant blood disorders, while also serving as a broader national resource for the wider nonmalignant hematology research community.

At its core, the HCCC is expected to provide program-wide administrative, operational, and communications infrastructure so the CCEHs can function as an integrated consortium rather than isolated sites. That central role typically includes organizing and supporting consortium governance and meetings, maintaining consistent communication across centers, facilitating sharing of information and resources, tracking progress and milestones, and ensuring that collaborative activities stay aligned with program goals. Because this is a cooperative agreement, NIH (NIDDK) is anticipated to have substantial involvement in the program’s coordination and oversight, meaning the HCCC would not simply run an independent project but would actively collaborate with NIH staff and the funded centers to manage and advance the consortium’s collective agenda.

A major required function of the HCCC is to operate a Pilot and Feasibility Program. This component is meant to seed smaller, early-stage research efforts that can generate preliminary data, test novel ideas, or create new collaborations, with the explicit intention that successful pilots will grow into larger, more definitive research projects later on. In practical terms, the HCCC would be responsible for running a fair and transparent process to solicit pilot proposals, coordinate scientific review, manage awards, monitor pilot progress, and help ensure that the pilot program supports the consortium’s overarching mission in nonmalignant hematology and/or normal blood formation.

The opportunity is listed under the NIH CFDA number 93.847 and falls within health-related research (noted in the source as the funding activity category of Food and Nutrition, Health). While the notice is specifically about building and running the coordinating center, the scientific scope is clearly anchored to nonmalignant hematologic diseases and the biology of hematopoiesis, emphasizing multidisciplinary collaboration across the national research effort in this space. Importantly, the FOA is marked “Clinical Trial Not Allowed,” which means applicants must structure proposed activities so they do not meet NIH’s definition of a clinical trial; the work should focus on coordination, infrastructure, collaboration, and pilot activities that remain outside clinical trial conduct as defined by NIH policy.

Eligibility is broad and includes many types of domestic organizations and government entities. Eligible applicants include state, county, and city/township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations that are not federally recognized tribal governments; public housing authorities/Indian housing authorities; nonprofits with and without 501(c)(3) status (other than institutions of higher education); for-profit organizations (other than small businesses); and small businesses. The FOA also explicitly highlights additional eligible applicant types such as historically black colleges and universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian serving institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), faith-based or community-based organizations, eligible federal agencies, regional organizations, tribal governments that are not federally recognized, and U.S. territories or possessions. Foreign institutions (non-U.S. entities) are not eligible to apply as the applicant organization, but non-U.S. components of U.S. organizations may participate, and foreign components (as defined in the NIH Grants Policy Statement) are allowed.

From an administrative standpoint, the source information indicates the FOA was created on 2019-09-19 and had an original closing date of 2019-11-21. The award ceiling and expected number of awards are not specified in the provided excerpt. Overall, the opportunity is best understood as funding for a consortium-level coordinating and enabling structure, where success is measured by how effectively the HCCC integrates the hematology centers, builds community-facing resources and communication channels, and runs a pilot program that reliably produces new, fundable research directions for the nonmalignant hematology field.

• The National Institutes of Health in the food and nutrition, health sector is offering a public funding opportunity titled "NIDDK Hematology Central Coordinating Center (U24 Clinical Trial Not Allowed)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847.
• This funding opportunity was created on 2019-09-19.
• Applicants must submit their applications by 2019-11-21. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for RFA DK 19 013

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