Opportunity Information: Apply for RFA HL 17 030
Revision Applications for Regenerative Medicine Innovation Projects (RMIP) (R24) is a National Institutes of Health (NIH) funding opportunity, issued in coordination with participating NIH Institutes and Centers and the U.S. Food and Drug Administration (FDA), that supports competing revision applications to existing, active R24 awards. The core idea is not to start a brand-new standalone project, but to expand the scope, activities, or research protocol of an already funded R24 regenerative medicine project during the current budget period by requesting an increase in support. In practical terms, the FOA is aimed at teams that already have an R24 infrastructure or program in place and want to add new work that meaningfully extends what the parent award is doing.
The scientific focus is clinical research that advances regenerative medicine using adult stem cells. The FOA is framed around well-recognized bottlenecks in the field, especially the translational hurdles that can slow down or complicate the path from a promising regenerative concept to a safe, effective, and reproducible therapy. Projects are expected to be innovative and solution-oriented, meaning they should tackle problems that have broad relevance across regenerative medicine development rather than narrow, one-off issues.
A major emphasis is placed on product development challenges that matter for regulatory submissions, reflecting FDA involvement and the real-world need to generate evidence and processes that can support eventual clinical and regulatory decision-making. The opportunity highlights the need for improved tools, methods, standards, and applied science that strengthen how regenerative medicine products are manufactured and evaluated. Examples of the kinds of issues this can include are better approaches to manufacturing and scale-up, more reliable quality assessments, stronger characterization of the product, and improved methods to assess or predict safety and effectiveness. Overall, the intent is to help the field develop a clearer, more rigorous, and more consistent foundation for evaluating adult stem cell-based regenerative therapies.
From an eligibility standpoint, the FOA is broadly inclusive across government, academic, nonprofit, and industry organizations, including state and local governments, public and private institutions of higher education, tribal governments and tribal organizations, public housing authorities/Indian housing authorities, nonprofit organizations with or without 501(c)(3) status, for-profit organizations (other than small businesses), and small businesses, with a note to consult the announcement text for any additional eligibility details. However, the defining eligibility constraint is that applicants must be investigators with active R24 research project awards, because the mechanism being offered is a competing revision rather than a new award.
Administratively, this is a discretionary grant opportunity from the U.S. Department of Health and Human Services (HHS) through NIH. The funding opportunity number is RFA-HL-17-030. It was created on April 28, 2017, with an original closing date of June 26, 2017. The announcement anticipated making about 6 awards, with an award ceiling listed at $324,500. The FOA is associated with multiple CFDA numbers spanning NIH programs (including 93.121, 93.173, 93.233, 93.242, 93.286, 93.350, 93.837, 93.838, 93.839, 93.840, 93.846, 93.847, 93.853, 93.855, 93.856, 93.866, 93.867), reflecting participation across different NIH components.
Taken together, this opportunity is designed for existing NIH R24 regenerative medicine teams that are positioned to extend their work into high-impact, clinically relevant directions, especially those that generate practical advances in manufacturing, quality, safety, and effectiveness evaluation that can stand up in a regulatory context and help move adult stem cell-based regenerative therapies closer to responsible clinical use.Apply for RFA HL 17 030
- The Department of Health and Human Services, National Institutes of Health in the food and nutrition, health sector is offering a public funding opportunity titled "Revision Applications for Regenerative Medicine Innovation Projects (RMIP) (R24)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121, 93.173, 93.233, 93.242, 93.286, 93.350, 93.837, 93.838, 93.839, 93.840, 93.846, 93.847, 93.853, 93.855, 93.856, 93.866, 93.867.
- This funding opportunity was created on Apr 28, 2017.
- Applicants must submit their applications by Jun 26, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $324,500.00 in funding.
- The number of recipients for this funding is limited to 6 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Applicants who have applied for this opportunity (RFA HL 17 030) also looked into and applied for these:
| Funding Opportunity |
|---|
| Revision Applications for Regenerative Medicine Innovation Projects (RMIP) (U01) Apply for RFA HL 17 034 Funding Number: RFA HL 17 034 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $324,500 |
| Revision Applications for Regenerative Medicine Innovation Projects (RMIP) (P41) Apply for RFA HL 17 033 Funding Number: RFA HL 17 033 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $324,500 |
| Cystic Fibrosis Research and Translation Center (P30) Apply for RFA DK 17 007 Funding Number: RFA DK 17 007 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $750,000 |
| NIDDK Information Network Coordinating Unit: dkNET-CU (U24) Apply for RFA DK 17 010 Funding Number: RFA DK 17 010 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $635,000 |
| Limited Competition for the Continuation of the Drug Induced Liver Injury Network Data Coordinating Center (U24) Apply for RFA DK 17 510 Funding Number: RFA DK 17 510 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $900,000 |
| Limited Competition for the Continuation of the Drug Induced Liver Injury Network (DILIN) Clinical Centers (U01) Apply for RFA DK 17 509 Funding Number: RFA DK 17 509 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $250,000 |
| Chronic Kidney Disease in Children Central Biochemistry Laboratory (U24) Apply for RFA DK 17 034 Funding Number: RFA DK 17 034 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $250,000 |
| Catalyst Award in Diabetes, Endocrinology and Metabolic Diseases (DP1- Clinical Trial Not Allowed) Apply for RFA DK 17 011 Funding Number: RFA DK 17 011 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $500,000 |
| NIDDK Partnerships with Professional Societies to Enhance Scientific Workforce Diversity and Promote Scientific Leadership (R25) Apply for RFA DK 17 015 Funding Number: RFA DK 17 015 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $135,000 |
| Diabetic Foot Consortium - Clinical Research Units (U01) Apply for RFA DK 17 014 Funding Number: RFA DK 17 014 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $275,000 |
| Lymphatics in Health and Disease in the Digestive System (R01 - Clinical Trials Not Allowed) Apply for RFA DK 17 016 Funding Number: RFA DK 17 016 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $499,999 |
| Multidisciplinary Urologic Research (KURe) Career Development Program (K12 Clinical Trial Optional) Apply for RFA DK 17 012 Funding Number: RFA DK 17 012 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $600,000 |
| George M. O'Brien Urology Cooperative Research Centers Program (U54-Clinical Trial Optional) Apply for RFA DK 17 013 Funding Number: RFA DK 17 013 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $1,000,000 |
| Silvio O. Conte Digestive Diseases Research Core Centers (P30 Clinical Trial Optional) Apply for RFA DK 18 001 Funding Number: RFA DK 18 001 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $750,000 |
| Funding For Collaborative Clinical Research In Type 1 Diabetes: Living Biobank (R01 Clinical Trial Optional) Apply for RFA DK 17 032 Funding Number: RFA DK 17 032 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $600,000 |
| Elucidating the Effect of Glycemic Excursions on Patient Well-being and Cognitive Status in People with Type 1 Diabetes (T1D) (R01 Clinical Trial Optional) Apply for RFA DK 18 003 Funding Number: RFA DK 18 003 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $500,000 |
| Undergraduate Summer Research Education in Kidney, Urologic, and Hematologic Diseases (R25 Clinical Trial Not Allowed) Apply for RFA DK 18 006 Funding Number: RFA DK 18 006 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $125,000 |
| Human Islet Research Enhancement Center for the Human Islet Research Network (U24 Clinical Trial Not Allowed) Apply for RFA DK 18 012 Funding Number: RFA DK 18 012 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $1,200,000 |
| Ancillary Studies to the NIDDK Inflammatory Bowel Disease Genetics Consortium (R01- Clinical Trial Optional) Apply for RFA DK 18 017 Funding Number: RFA DK 18 017 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $200,000 |
| Lymphatics in Health and Disease in the Digestive System (R01 Clinical Trial Not Allowed) Apply for RFA DK 18 021 Funding Number: RFA DK 18 021 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $250,000 |
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